World Journal of Surgical Medical and Radiation Oncology Volume No 6

Case Report Open Access

Lymphoplasmacyte –rich meningioma –A rare case report and review of literature

Akriti Kashyap, Tanushree Mukherjee and Rahul Dev Chauhan
World Journal of Surgical Medical and Radiation Oncology 2017, 6:4

Abstract

Background

Lymphoplasmacyte –rich meningioma is a very rare pathological entity which is included under WHO grade -1 meningiomas .These meningiomas are characterised by abundant lymphoplasmacytic infiltrate which overshadows the underlying the meningothelial component.

Case Presentation

:A 27 year old lady who presented with headache of 15 days duration and generalised tonic clonic seizures of one day duration. Her clinical, haematological and biochemical profile showed no abnormality. However MRI brain revealed a well –defined extra axial dura based mass in the right fronto-parietal convexity, possibly a meningioma. She was subsequently diagnosed as a case of lympho plasmacyte-rich meningioma,WHO grade -1 after histopathological examination.

Conclusions

Lymphoplasmacyte –rich meningiomas can have varied clinical manifestations and must be distinguished from other entities like idiopathic hypertrophic pachymeningitis and inflammatory pseudotumor which commonly affect the meninges and display a similar histopathological picture. Therefore correlation with MRI findings and further evaluation in the form of immunohistochemistry markers is required to reach a definitive diagnosis. However, neoplastic versus inflammatory nature of these meningiomas has to be ascertained and requires further research on the subject.

Key words

lymphoplasmacyte , meningioma , MRI, neoplasm, inflammatory




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