World Journal of Surgical Medical and Radiation Oncology Volume No 7

Review Open Access

Brachial Plexopathy Due to Breast Cancer Metastasis: Report of a Case and Systematic Review of Literature

Pandey Manoj and Shukla Mridula
World Journal of Surgical Medical and Radiation Oncology 2018, 7:3

Abstract

Background

Metastatic Brachial plexopathy is a rare and significant cause of morbidity in patients with breast cancer that is increasingly being diagnosed with use of FDG PET scanning.

Case Report

A 55 year old women presented with pain in the shoulder and arm 5 years after undergoing bilateral mastectomy for infilterating ductal carcinoma. MRI and PET scan confirmed metastasis to brachial plexus and liver. Biopsy from the brachial plexus and immunohitochemistry confirmed it to be metastasis from breast cancer. Patient was treated with chemotherapy and is alive with disease.

Methods of review

A literature search was carried out on Pubmed using a definite search strategy.

Results

Using the Prisma guidelines and after the review of abstract 23 relevant studies were identified. Six studies were identified by back reference and cross references from these articles. Thus identified total 29 articles are reviewed.

Conclusions

Metastatic involvement of brachial plexus is rare and is often part of disseminated disease elsewhere. Radiotherapy and systemic therapy is the treatment of choice. The prognosis is often poor and pain control is optimum with use of multimodal treatment.

Key words

Breast cancer; metastasis; chemotherapy; PET scan; radiotherapy; prognosis; imaging




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