World Journal of Pathology Volume No 8

Case Report Open Access

Non – Functioning Adrenocortical Carcinoma – Report of a Case and Review of Literature

Nagarekha Kulkarni
World Journal of Pathology 2017, 6:8



Adrenocortical carcinomas (ACC) are rare aggressive tumors with poor prognosis. Their annual incidence is 0.6 – 1.67 cases per million population per year.

Case Presentation

A 48 yrs old male presented with pain per abdomen and a palpable mass on the left hypochondrium with radiating pain in the left lower limb and left side of scrotum.  US, CT abdomen and pelvis revealed well defined heterogeneous mass lesion measuring 14 x 12 cms noted in the left suprarenal region. Adrenal gland was not visualized separately. Left kidney was displaced inferiorly. Hormonal assay, renal function test were normal. Left adrenalectomy was done and histopathologic examination revealed adrenocortical carcinoma – non functional.


ACC is a rare aggressive tumor with poor prognosis. In the present case pressure symptoms was an early manifestation. Any patient presenting with the pressure symptoms should be investigated and treated at the earliest, as early diagnosis increases the chances of long time survival.

Key Words

Left hypochondrium, adrenocortical carcinoma, heterogeneous

Download PDF    Full Text