World Journal of Pathology Volume No 6

Case Report Open Access

Low Grade Endometrial Stromal Sarcoma of Ectocervix: Report of a Case and Review of Literature

Reema Bhushan, Shilpi Agarwal and Sangeeta Pahuja
World Journal of Pathology 2017, 6:5

Abstract

Background

Endometrial stromal sarcomas (ESS) are rare malignant tumors of the uterus. The primary tumour can occur in extra-uterine sites like ovary, fallopian tube, cervix, vulva, vagina, omentum and retro peritoneum. Primary low grade ESS occurring in ectocervix is reported very rarely. Primary tumour in the cervix mimics a fibroid polyp and poses a diagnostic dilemma.

Case Presentation

We report a case of 43 years old perimenopausal lady who presented with bleeding per vaginum and cervical polyp. Ultrasound revealed uterine leiomyoma in addition to the cervical polyp. Histological examination revealed epithelioid cell tumour. The diagnostic challenge was to differentiate ESS from epithelioid leiomyoma and PEcoma for which immunohistochemistry was carried out which showed positivity for Cluster of Differentiation 10 (CD10), Estrogen Receptor (ER), Progesterone Receptor (PR), Wilms’ Tumor 1 (WT1), Cytokeratin (CK) and Vimentin .

Conclusions

The case report emphasises the need to include ESS in the differential diagnosis of cervical polyp.

Key words

Vaginal bleeding; dysfunctional bleeding; leiomyoma; cervical polyp; epitheloid cell tumor; stromal sarcoma




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