Original Article

Second Malignant Neoplasms in Survivors of Childhood Cancer

^1,Ray M. Merrill,  ²Arielle A. Sloan

• ¹Department of Health Science, College of Life Sciences, Brigham Young University, Provo, Utah

• Submitted:Wednesday, March 12, 2014
• Accepted:Saturday, April 19, 2014
• PublishedThursday, May 01, 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited

Abstract

Introduction

 Individuals who survive a first primary cancer in childhood are at increased risk of a second neoplasm.

Study design

This cohort study updates a previous report with 10 additional years of data to verify and add to our existing knowledge about subsequent cancer risk.

Materials and Methods

Analyses are based on a cohort of 40,337 children (age<20 years) who survived cancer for at least two months from 1973 through 2010 in the Surveillance, E